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Get emergency medical help if you have any of these signs of an allergic reaction to Pramipexole: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Pramipexole and call your doctor at once if you have any of these serious side effects:

• extreme drowsiness, falling asleep suddenly, even after feeling alert;
• nausea, sweating, feeling light-headed, fainting;
• hallucinations;
• muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine;
• chest pain, cough with white or pink phlegm (mucus), wheezing;
• feeling short of breath (even with mild exertion), swelling, rapid weight gain;
• feeling weak or tired, loss of appetite, rapid weight loss;
• fast or uneven heartbeats; or
• tremors, twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

Less serious Pramipexole side effects may include:

• dry mouth, stomach pain, vomiting, constipation;
• headache, dizziness, spinning sensation;
• mild drowsiness;
• swelling in your hands or feet;
• appetite or weight changes;
• blurred vision;
• sleep problems (insomnia), unusual dreams;
• amnesia, forgetfulness, thinking problems; or
• impotence, loss of interest in sex, or trouble having an orgasm.

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Some patients may also have a fever. The National List is March 15, 2023.